Anti-PYCARD Polyclonal Antibody
产品名称： Anti-PYCARD Polyclonal Antibody
英文名称： Anti-PYCARD Polyclonal Antibody
产品编号： K002239P
产品价格： null
产品产地： 北京
品牌商标： solarbio
更新时间： 2025-05-30T15:53:18
使用范围： WB IHC IF
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
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Anti-PYCARD Polyclonal Antibody
品牌：solarbio | 货号：K002239P
| 英文名称 | Anti-PYCARD Polyclonal Antibody |
|---|---|
| 别名 | ASC;CARD5;TMS;TMS-1;TMS1 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 29108 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PYCARD |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PYCARD |
| Subcellular Locations | Cytoplasm Endoplasmic reticulum Mitochondrion Nucleus |
| Swiss Prot | Q9ULZ3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |